December

December 24, 2017

Natural product therapy for Non-alcoholic fatty liver disease (NAFLD): Rosmarinic acid, isolated from Rosemary officinalis, and Perilla frutescens,  promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 24/December/2017, 11.51 pm

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]
December 24, 2017

Molecular therapy for Deafness: A therapeutic mix encompassing Moxonidine, Cholecalciferol, Ajoene and DIM (MOCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 24/December/2017, 11.43 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Molecular therapy for Deafness: A therapeutic mix encompassing Moxonidine, Cholecalciferol, Ajoene and DIM (MOCAD)  increases the expression […]
December 23, 2017

Molecular therapy for Diabetic retinopathy: Dimethyl Fumerate (DMF) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 24/December/2017, 1.10 am

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for […]
December 23, 2017

Molecular therapy for TIIDM and obesity-associated metabolic deficits: A pharmaceutical mixture (PMSFN) encompassing Pyridoxamine (PM) and Sulforaphane (SFN)  increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 24/December/2017, 1.01 pm

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that […]