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January 17, 2018

Lifespan extension therapy: Panaxynol, isolated from American ginseng,  may increase life span via up-regulation of its target gene BubR1, 17/January/2017, 10.02 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
January 17, 2018

Activation of the PD-1 pathway for Pain therapy: Sildenafil [Phosphodiesterase-5 inhibitor], a drug used in the treatment of erectile dysfunction and pulmonary arterial hypertension,  increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 17/January/2017, 1.29 pm

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
January 17, 2018

Molecular therapy for body weight control, energy homeostasis and TIIDM: Melatonin, a hormone that regulates sleep and wakefulness, increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 17/January/2018, 10.10 am

Introduction: What they say A study from the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA shows that “Regulation of circadian behaviour […]
January 17, 2018

Natural product-based therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing Lovastatin, Epicatechin and Matrine (LSEM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 17/January/2018, 9.56 am

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for […]