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January 18, 2018

Vitamin-based therapy for body weight control, energy homeostasis and TIIDM: A pharmaceutical mixture (PMSF) encompassing Pyridoxamine (PM) and Sildenafil (SF)  inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 18/January/2017, 12.27 pm

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
January 18, 2018

Natural product-based therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing 15-Deoxy-Delta-12,14-prostaglandin J2 (15d-PGJ2), Epicatechin and Matrine (15d-GJ2EM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 18/January/2018, 12.05 pm

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for […]
January 18, 2018

Vitamin-based therapy for body weight control, energy homeostasis and TIIDM: A pharmaceutical mixture (PMSF) encompassing Pyridoxamine (PM) and Sildenafil (SF) decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 18/January/2017, 11.54 am

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
January 18, 2018

Lifespan extension therapy:  Sildenafil (brand name: Viagra, Revatio and others), used in the treatment of erectile dysfunction and pulmonary arterial hypertension, increases life span via up-regulation of its target gene BubR1, 18/January/2018, 11.46 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]