January

January 20, 2018

Molecular therapy for tuberculosis: Sildenafil, a drug used in the treatment of erectile dysfunction and pulmonary arterial hypertension, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 20/January/2018, 11.26  pm

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
January 20, 2018

Anti-infective Therapy:  A pharmaceutical mixture encompassing Azithromycin and Aspirin inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 20/January/2018,  11.07 pm

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]
January 20, 2018

Natural product-therapy for Deafness: A therapeutic mix encompassing Tadalafil, Cholecalciferol, Ajoene and DIM (TCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 20/January/2018, 10.57 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Natural product-therapy for Deafness: A therapeutic mix encompassing Tadalafil, Cholecalciferol, Ajoene and DIM (TCAD)  increases the expression […]
January 20, 2018

Molecular therapy for Metastatic cancers: Metformin, an anti-hyperglycemic drug, increases the expression of tumor/metastatic suppressors TPM1 and TAp63, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 20/January/2018, 10.47 pm

From significance of the study to Public health relevance:  Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]