January

January 13, 2018

Natural product-based therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing Atorvastatin, Epicatechin and Matrine (ANEM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 13/January/2018, 11.34 pm

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for […]
January 13, 2018

Lifespan extension therapy:  Prostaglandin D2 (PGD2) may increase life span via up-regulation of its target gene BubR1, 13/January/2017, 11.33 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
January 13, 2018

Lifespan extension therapy: Allicin, one of the main components of Garlic, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 10/January/2017, 11.32 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
January 13, 2018

Molecular therapy for Metastatic cancers: Torasemide, an anti-hypertensive drug, increases the expression of tumor/metastatic suppressors GRHL3 and long ncRNA GAS5, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 13/January/2017, 11.20 pm

From Significance of the study to Public health relevance:  Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]