January

January 3, 2018

Natural product-derived PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy in Glioblastoma: A therapeutic mix encompassing Geldanamycin, 5-Azacitidine, Temozolomide, Cerivastatin, Salinomycin, &, Fluoxetine (GATCSF) inhibits oncoproteins EGFR, and Bcl-xl expression, increases tumor suppressor p53 expression, inhibits glioblastoma proliferation, increases interferon-IFNγ signalling, increase antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 3/January/2018, 9.23 am

Introduction:What they say: A recent study from Department of Molecular and Medical Pharmacology, David Geffen UCLA School of Medicine, Los Angeles, California, USA; Jonsson Comprehensive Cancer […]
January 1, 2018

Vitamin-based regenerative therapy for reversing diabetes: A pharmaceutical mixture encompassing  Pyridoxamine, Calcitriol, Folic acid, and Ascorbic acid (PMCFAAA) increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 1/January/2018, 4.20 pm

Introduction: What they say A study from the Longevity Institute, School of Gerontology, Department of Biological Sciences, University of Southern California, 3715 McClintock Avenue, Los Angeles, […]
January 1, 2018

Natural product-based Lifespan extension therapy: A pharmaceutical mixture encompassing Chrysin and α-linoleic acid increases life span via up-regulation of its target gene BubR1, 1/January/2018, 9.00 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
January 1, 2018

Molecular therapy for inflammation and arthritis: A pharmaceutical mixture encompassing Calcitriol and  TNF-α (CAT)  increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up-regulation of its target genes, 1/January/2018, 8.46 am

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that […]