January 29, 2018

Lifespan extension therapy: Omeprazole (Brand name: Prelosec, Losec), a drug used in the treatment of stomach ulcers, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 29/January/2017, 11.02 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
January 29, 2018

Molecular therapy for anxiety and depression: Isorhapontigeninn, isolated from  Norway spruce, and Sitka spruce among others , decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 29/January/2018, 10.52 pm

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
January 29, 2018

Molecular therapy for pulmonary arterial hypertension: Rampril (brand name: Altace), an angiotensin-converting enzyme inhibitor used to treat high blood pressure and myocardial disorders, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 29/January/2018, 10.42 pm

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
January 28, 2018

Molecular therapy for body weight control, energy homeostasis and TIIDM: Omeprazole(brand name: Prelosec, Losec), a drug used in the treatment of stomach and duodenal ulcers,  increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 28/January/2018, 11.08 pm

Introduction: What they say A study from the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA shows that “Regulation of circadian behaviour […]