Serotonin the happy hormone comes to the rescue of blood sugar disease: Serotonin-based adjunct therapy for autoimmune diabetes (TIDM): Serotonin (5-hydroxytryptamine (5-HT)), a mono neurotransmitter known to play a role in mood, anxiety and depression, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 27/May/2018, 6.41 am
Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical Sciences, University of Milan, Milan 20157, Italy; and Nephrology Division, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA shows that “PD-L1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor […]
Sleeping your way to live free of cardiac diseases: Melatonin-based therapy for Cardiomyopathy: Melatonin ( N-acetyl-5-methoxy tryptamine), a hormone known to regulate sleep and wakefulness, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy, via up regulation of its target gene, 25/May/2018, 7.29 pm
Introduction: What they say A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart function through microRNA-mediated Sox6 repression.” This study was published, in the 2 June 2015 issue of the journal “Nature Genetics” (the number 1 research journal in Genetics with an impact factor of 29.648), by Prof. Da-Zhi Wang & Jian Ding, and […]
A salty way to keep the cardiac diseases at bay-hard to believe though(!): Hypertonic saline-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: Hypertonic saline (10%) increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 23/May/2018, 12.58 am
Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was published, in the 6 April 2015 issue of the journal “Nature cell biology” (the number 1 journal in “Cell biology” research with an impact factor of 20.761), by Prof Tzahor E, D’Uva E, and others. What […]
A fibrous way to strengthen your heart and extend lifespan: β-glucan-based therapy for cardiomyopathy: β-glucan, found abundantly in oats and barley, may suppress tumor suppressor INK4a/p16 expression, inhibit dilated cardiomyopathy and extend life span, via up regulation of its target gene, 23/May/2018, 12.37 pm
What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: A fibrous way to strengthen your heart and extend lifespan: β-glucan-based therapy for cardiomyopathy: β-glucan, found abundantly in oats and barley, may suppress tumor suppressor INK4a/p16 expression, inhibit dilated cardiomyopathy and extend life span, via up regulation of its target gene From the Significance of the […]
A handful of fiber-rich Oats and barley a day keeps the cardiac diseases at bay: Fiber-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: β-glucan, found abundantly in Oats and barely, increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 23/May/2018, 12.10 am
Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was published, in the 6 April 2015 issue of the journal “Nature cell biology” (the number 1 journal in “Cell biology” research with an impact factor of 20.761), by Prof Tzahor E, D’Uva E, and others. What […]
A salty way to say no to pain: Hypertonic saline-based Pain therapy: Hypertonic saline (10%) increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 22/May/2018, 11.48 pm
Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China; and Department of Neurobiology, Duke University Medical Center, Durham, North Carolina, US, shows that “PD-L1 inhibits acute and chronic pain by suppressing nociceptive neuron […]
