May 17, 2018

cAMP-based adjunct therapy for autoimmune diabetes (TIDM): Dibutyryl cAMP (DBcAMP), an analog of cAMP, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 17/May/2018, 7.45 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical […]
May 17, 2018

Amylin-based therapy for glucose homeostasis and TIIDM: Amylin, a peptide hormone, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 17/May/2018, 7.24 pm

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
May 17, 2018

A sweet way to lengthen lifespan-too good to be true(!): Oligofructose-based therapy for life-span extension: Agavin (Oligofructose), a new natural sugar isolated from agavi, may  increase insulin sensitivity, slow down cardiac aging, and increase life span, via up-regulation of BubR1 and others genes, 17/May/2018, 6.20 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
May 16, 2018

Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Hydrogen-rich saline increases the expression of tumor suppressors genes, such as p53, TA-p73 and TA-p63, GRHL3 and long ncRNA GAS5, and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 16/May/2017, 3.55 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]