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June

June 29, 2018

A vaccine for lowering cholesterol, and triglycerides levels: Repurposing tuberculosis BCG vaccine into a cholesterol-lowering vaccine that inhibits Non-alcoholic fatty liver disease (NAFLD): BCG vaccine promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD, via down regulation of its target gene, 30/July/2018, 12.18 am

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]
June 29, 2018

Bacillus Calmette Guerin (BCG) vaccine-based therapy for Diabetic retinopathy: BCG vaccine inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 29/June/2018, 11.15 am

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for […]
June 29, 2018

Broccoli for enhanced learning, memory, cognition and longevity: Sulforaphane from broccoli functions as a learning/memory/cognitive/longevity-enhancer: Sulforaphane, isolated from broccoli among others, increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down regulation of its target genes, 29/June/2018, 10.58 am

Introduction: What they say: A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center […]
June 29, 2018

Bacillus Calmette Guerin (BCG) vaccine-based therapy for TIIDM and Metabolic defects: BCG vaccine increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 29/June/2018, 10.45 am

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC […]