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August 13, 2018

Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: PCGF2/Mel-18 increases the expression of tumor suppressors genes, such as  TPM1, INK4a/ARF, TA-p73, TA-p63, p53, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 13/August/2018, 10.41 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
August 13, 2018

Contraceptive pills may aid in the treatment of blood-stage Plasmodium infection: Progestin, one of the components of birth control/contraceptive pills, decreases the expression of CTLA-4, PD-L1, and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria via upregulation of its target gene, 13/August/2018, 6.52 pm

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that […]
August 13, 2018

An aspirin a day keeps HIV1-infections at bay: Aspirin, an analgesic/antipyretic drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via upregulation of its target gene, 13/August/2018, 6.28 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: An aspirin a day keeps HIV1-infections at bay: Aspirin, an analgesic/antipyretic drug, increases Heme […]
August 13, 2018

Birth control/contraceptive pills as anti-infective agents:  17-α-Ethynylestradiol, one of the main components of contraceptive/birth control pills, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene 131/August/2018, 6.11 pm

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]