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August 18, 2018

Revealing the unrevealed function of  the reproductive hormone Relaxin in the heart: Relaxin, a protein hormone that facilitates labor and relaxes the uterine musculature, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of PNUTS, 19/August/2018, 12.35 am

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of the […]
August 18, 2018

Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Emodin, isolated from Rhubarb and others,  increases the expression of tumor suppressors genes, such as  Smad7, p12DOC1/CDK2AP1, TA-p73, TAp63, p53, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 19/August/2018, 12.13 am

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
August 18, 2018

Reproductive hormone aids in the treatment of blood sugar disease: Relaxin-based therapy for DM: Relaxin, a reproductive hormone, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of  its target gene Lin28, 19/August/2018, 12.07 am

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]
August 18, 2018

Insulate your heart against cardiac dysfunction with H.Pylori CTB-UE vaccine: H.Pylori CTB-UE vaccine-based adjunct therapy for cardiac hypertrophy and fibrosis: H.Pylori CTB-UE vaccine decreases MiR-29 expression, activates Wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1 and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function via upregulation of its target gene, 18/August/2018, 11.41 pm

Introduction: What they say:   A recent study from the Institute of Pharmacology and Toxicology, Technical University Munich (TUM), 80802, Munich, Germany; DZHK (German Center for Cardiovascular […]