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August 23, 2018

Thyroid hormones come to the rescue of blood sugar disease: Levothyroxine (T4) and Liothyronine(T3)-based therapy for autoimmune diabetes (TIDM): Thyroxine/Levothyroxine (T4) and Liothyronine/Triiodothyronine (T3) increase PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 23/August/2018, 11.35 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical […]
August 23, 2018

Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: PCGF2/Mel-18 increases the expression of tumor suppressors genes, such as  IGFBP3, PIAS3, p53, TAp63, TAp73, INK4a/ARF, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 23/August/2018, 2.58 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
August 23, 2018

Reproductive hormone protects against cardiac diseases: Relaxin-based therapy for Cardiomyopathy:  Relaxin, a protein hormone that facilitates labor and relaxes the uterine musculature, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy, via up-regulation of its target gene, 23/August/2018, 2.54 pm

Introduction: What they say   A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart […]
August 23, 2018

A Lotus way to lengthen lifespan: The Lotus component Nucinferin-based therapy for life-span extension: Nucinferin, isolated from lotus leaf, may  increase insulin sensitivity, slow down cardiac aging, and increase lifespan, via up-regulation of BubR1 and others genes, 23/August/2018, 2.36 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston, USA; […]