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September 21, 2018

A derivative of sulfamoylated Estrone comes to the rescue of anxiety and depression: 2-Ethylestrone-3-O-sulfamate (2EtEMATE) decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression, via down-regulation of its target gene, 21/September/2018, 11.00 pm

Introduction: What they say:  A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
September 21, 2018

Probiotics as anti-infective agents:  Probiotics-based adjunct therapy for viral and bacterial infections: Probiotic Lactobacillus Rhamnosus inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene, 21/September/2018, 10.29 pm

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]
September 21, 2018

Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Mibolerone (Trade name: Cheque drops and Matenon), an anabolic-androgenic steroid, increases the expression of tumor suppressors genes, such as IGFBP3, PIAS3, p53,  p53, TAp63, TAp73, INK4a/ARF, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 21/September/2018, 10.02 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
September 21, 2018

Natural product-based therapy for anxiety and depression: Oroxyloside (OAG), a metabolite of Oroxylin A derived from the root of Scutellaria baicalensis Georgi,  decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression, via down-regulation of its target gene, 21/September/2018, 6.20 pm

Introduction: What they say:  A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]