September

September 7, 2018

Molecular therapy for an enhanced, extended, and healthy lifespan: Lobeglitazone (trade name: Dovie), an anti-hyperglycemic agent, increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 7/September/2018, 11.59 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
September 5, 2018

Act(os) against cancer: Pioglitazone (trade name: Actos), an anti-diabetic drug, increases the expression of tumor suppressors genes, such as PIAS3, IGFBP3, p53,  p53, TAp63, TAp73, INK4a/ARF, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 5/September/2018, 11.14 am

Teacher’s day special ********* We wish everyone a happy Teacher’s day. On this special occasion, we are happy to announce that ideas posted today (05/September/2017) will be available to […]
September 5, 2018

Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: PCGF2/Mel-18 increases the expression of tumor suppressors genes, such as  PTPN14, Rb, p53, TAp63, TAp73, INK4a/ARF, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 5/September/2018, 11.07 am

Teacher’s day special ********* We wish everyone a happy Teacher’s day. On this special occasion, we are happy to announce that ideas posted today (05/September/2017) will be available to […]
September 5, 2018

Consuming one dark chocolate bar a day strengthen your heart: Dark chocolate-based therapy for cardiomyocyte proliferation and heart regeneration: Dark chocolate decreases tumor suppressor Mir-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 5/September/2018, 10.30am

Teacher’s day special ********* We wish everyone a happy Teacher’s day. On this special occasion, we are happy to announce that ideas posted today (05/September/2017) will be available to […]