The tiny probiotic Probiotic lactobacillus reuteri  BM36301  may extend the lifespan of mighty humans: Probiotic lactobacillus reuteri  BM36301 inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan, 25/November/2018, 7.41 am

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What they say:

A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.” This study was published, in the 2 October 2009 issue of the Journal “Science” (I.F: 31.477 ), by Prof Dominic J. Withers, Dr. Selman C and others.


What we say: 

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports, for the first time, that:  The tiny probiotic Probiotic lactobacillus reuteri  BM36301 may extend the lifespan of mighty humans: Probiotic lactobacillus reuteri  BM36301 inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan



Research findings to Therapeutic opportunity: 

Figure 1. Mechanistic insight into how Probiotic lactobacillus reuteri  BM36301 may extend lifespan.  Probiotic  Bacillus licheniformis inhibits p70 S6 kInase expression and promotes longevity

Figure 2. Probiotic lactobacillus reuteri  BM36301 functions as a longevity-promoter

 Probiotic lactobacillus reuteri  BM36301, by increasing the expression of its target gene, it may suppress Ribosomal protein S6 kinase 1 (p70S6 Kinase) expression. Thereby, it may promote: (1) resistance to bone, immune, and motor dysfunction; (2) insulin sensitivity; and (3) longevity (fig. 1).   

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Thus, pharmacological formulations encompassing “Probiotic lactobacillus reuteri  BM36301, either alone or in combination with any of the known longevity-promoting compound(s)” may be used to extend the lifespan of an individual (fig. 2).


Details of the research findings: 

Idea Proposed/Formulated (with experimental evidence) by:

Dr L Boominathan Ph.D.

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

Undisclosed mechanistic Information: How does Probiotic lactobacillus reuteri  BM36301 decrease the expression of p70 S6 Kinase?

# Research cooperation

Amount: $500#

For purchase and payment information, you may reach us at info@genomediscovery.org


References:

CitationBoominathan, L., The tiny probiotic Probiotic lactobacillus reuteri  BM36301  may extend the lifespan of mighty humans: Probiotic lactobacillus reuteri  BM36301 inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan, 25/November/2018, 7.41 am, Genome-2-BioMedicine Discovery center (GBMD), http://genomediscovery.org

Web: http://genomediscovery.org or newbioideas.com/

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