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December 6, 2018

A probiotic-based immune enhancement therapy: Probiotic Lactobacillus reuteri increases SOX2 expression, and promotes innate immunity against bacterial infection, via down-regulation of its target gene, 6/December/2018, 10.47 pm

Introduction: What they say:   A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in […]
December 6, 2018

A sweet way to treat Metastatic cancers: Xylobiose, a disaccharide of xylose, increases the expression of tumor/metastatic suppressors LATS1 and SMARCD4, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up-regulation of its target gene, 6/December/2018, 10.38 pm

From Significance of the study to Public health relevance:  Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
December 6, 2018

Probiotic-based chemotherapy for “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: A pharmaceutical composition encompassing Valsartan, a medication used in the treatment of high blood pressure and congestive heart failure, and Lactobacillus Rhamnosus increases the expression of tumor suppressors genes, such as PTPN14, p12DOC1, TA-p73/p63, p53 and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene , 6/December/2018, 3.24 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
December 6, 2018

Hot water immersion therapy for lowering cholesterol, and triglycerides levels: Hot water immersion (at 39C for 1 hour) decreases the levels of HMGCR,  triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 6/December/2018, 3.09 pm

The significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 […]