January

January 31, 2019

Molecular therapy for Diabetes Mellitus: CLOCK and BMAL1 augment the expression of FGF19 and FGF1,  attenuate hepatic glucose production, decrease hepatic acetyl CoA content, bring down the levels of plasma ACTH, and corticosterone, augment insulin sensitivity, promote weight loss and alleviate TIDM, via upregulation of its target gene, 31/January/2018, 11.51pm

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection […]
January 31, 2019

Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: LncRNA CUDR increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 31/January/2019, 11.29 pm

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]
January 31, 2019

Seladelpar (MBX8025/RWJ800025)-based therapy for Cardiac repair and myocardial infarction: Seladelpar (MBX8025/RWJ800025) increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up-regulation of its target gene, 31/January/2019, 11.14 pm

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, […]
January 31, 2019

Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: AIRE (Autoimmune regulator)  increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 31/January/2019, 10.51 pm

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]