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May 14, 2019

Mechanistic insights into how hunger hormone Ghrelin attenuates pain: Ghrelin, a peptide hormone that regulates appetite, food intake and others, increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 14/May/2019, 11.55 pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
May 14, 2019

Excess consumption of coffee during pregnancy increases the chances of childhood obesity: Caffeine increases the levels of HMGCR,  triglycerides, free cholesterol, and total cholesterol and accelerates the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 14/May/2019, 11.43 pm

The significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 […]
May 14, 2019

Natural sugar-based therapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing a pharmacological formulation encompassing Xylobiose (a disaccharide of xylose, with a  a beta-1,4-bond), and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as  HNF4α, CDK2AP1, E-cadherin, p53, and TA-p73/p63, stalls cell cycle progression, inhibits immune-inhibitory receptors/molecules, suppresses cancer stem cell proliferation, inhibits migration, invasion and metastasis of cancer cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 14/May/2019, 10.40 am

What we say: On the foundation of this interesting finding, Dr L Boominathan PhD, the Director-cum-chief Scientist of GBMD, reports that:  Natural sugar-based therapy targeting cancer […]
May 14, 2019

Have copious amount of deoxy sugar L-Rhamnose, not sucrose (table sugar), and stop worrying about lipid levels: L-Rhamnose (6-deoxy-L-Mannose) decreases the levels of HMGCR,  triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 14/May/2019, 9.51 am

The significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 […]