Solving a century-old puzzle as to how Mustard oil functions as a pain reliever: Mechanistic insights into how Mustard oil-derived compound  functions as a pain medication: A pharmaceutical mixture encompassing Allyl IsoThioCynate (AITC), derived from mustard seed or oil,  increases the expression of PD-L1, decreases the expression of Cox-2, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 23/June/2019, 11.19 pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China; and Department of Neurobiology, Duke University Medical Center, Durham, North Carolina, US shows that “PD-L1 inhibits acute and chronic pain by suppressing nociceptive neuron […]