July 5, 2019

Curing autoimmune diabetes  (TIDM) with HDAC (Histone deacetylase) inhibitors: Givinostat/Gavinostat-based therapy for autoimmune diabetes:Givinostat/Gavinostat, a histone deacetylase inhibitor used to treat systemic juvenile idiopathic arthritis,polycythaemia vera., Duchenne muscular dystrophy and others, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 5/July/2019, 11.19 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]
July 5, 2019

The tiny probiotic may increase the lifespan of mighty humans: Probiotic-based therapy for aging-associated diseases and Lifespan extension: Probiotic Lactobacillus plantarum AR501 inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 5/July/2019, 10.34 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
July 5, 2019

Where the peel is more valuable than the fruit (pulp): Citrus peel is enriched with longevity-promoting compounds than pulp: Citrus peel-based Lifespan extension therapy:  A pharmaceutical mixture encompassing Hesperidin, Tangeretin & Nobiletin (HTN), derived from citrus peel,  inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan by regulating the expression of its target genes, 5/July/2019, 10.17 pm

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]