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March 1, 2020

Repurposing the anti-allergic drug into a cardioprotective drug: Tranilast-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: Tranilast, an anti-allergy drug increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes, via up-regulation of its target gene, 1/March/2020, 5.43 pm

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]