A study from the Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA; Department of Pathology, Brigham and Women’s Hospital, Boston, USA has reported that “…MBD2 Supports Self-Renewal in Human Pluripotent Stem Cells.”
This study was published in the July 3, 2014 Cell Stem cell [I.F >27.361] by Prof. Marto JA, Lu Y and others from the Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA; Department of Pathology, Brigham and Women’s Hospital, Boston, USA.
On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Therapeuitc insights into targeting of cancer stem cells: Curcumin, the major component of turmeric, suppresses the expression of stem cell protein SFRS2 via up regulation of its target gene. This study offers mechanistic insights into how Curcumin, by up regulating its target gene, could inhibit the self-renewal and pluripotency networks in cancer stem cells. Together, this study suggests that pharmacological formulations encompassing “Curcumin or its analogues” can be used to to inhibit the proliferation of cancer stem cells.
Idea Proposed/Formulated by: Dr L Boominathan PhD
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Courtesy: When you cite drop us a line at info@genomediscovery.org
Citation: Boominathan, Therapeuitc insights into targeting of cancer stem cells: Curcumin, the major component of turmeric, suppresses the expression of stem cell protein SFRS2 via up regulation of its target gene, 22/July/2014, 9.14 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Web: http://genomediscovery.org
*Research cooperation