Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Insights into metabolism, Senescence, and ageing: MiRNA-429 increases the expression of longevity promoting gene Sirtuin-1 via down regulation of its target gene, 10/September/2014, 11.03 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests, for the first time, that MiRNA-429 may increase the expression of longevity-promoting gene product Sirtuin-1. Thus, pharmacological formulations encompassing “MiRNA-429 activator” may be used to (1) promote insulin sensitivity; (2) decrease ageing process; and (3) increase the life expectancy of an individual.