On the eve of Mahatma Gandhi Birth Anniversary
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We wish everyone a happy Mahatma Gandhi Jayanti 2014. On this special occasion, we are happy to announce that Ideas posted today (02/October/2014) will be available to the use of Scientists/Professors/Physicians/Researchers for free. So, there will be no terms and conditions for the ideas posted today (02/October/2014). Each idea posted will be served first come, first served basis. For more details, you may write to us at info@genomediscovery.org
Dr L Boominathan PhD
CEO & CSO, GBMD
The 1989 Nobel prize winner in Chemistry Prof. Thomas R. Cech from the University of Colorado BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; I.F: >42) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.” This study provides mechanistic insights into how TPP1 regulates telomerase function.
In connection with this finding, Dr Boominathan, Founder Director-cum-chief scientist of GBMD, reports that: MiRNA-based therapy for Human Cancer: BMP-4 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene. Remarkably, over 90% human tumors over express telomerase, suggesting that inhibition of its activity may increase the efficacy of anticancer therapy. Together, this study suggests that pharmacological formulations containing “BMP-4 activators or BMP-4-induced target miRNA“ can be used in the treatment of human cancers.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Web: http://genomediscovery.org
To cite: Boominathan, MiRNA-based therapy for Human Cancer: BMP-4 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene, 02/October/2014, 16.13, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Courtesy: When you cite drop us a line at info@genomediscovery.org
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