Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, Therapeutic insights into the treatment of hypertension, endothelial dysfunction and cardiovascular diseases: SMAD7 promotes endothelium-dependent vasorelaxation via up regulation of its target gene, 4/November/2014, 13.09, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Significance: This study suggests, for the first time, that SMAD7, by decreasing the expression of its target gene, it may rescue pulmonary arterial hypertension. Thus, pharmacological formulations encompassing “SMAD7 activators” may be used to treat pulmonary arterial hypertension.
Amount: $300*
* Research cooperation
Undisclosed information: A mechanistic insight into how SMAD7 rescues pulmonary arterial hypertension.
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* Research cooperation
Web: http://genomediscovery.org