Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Natural product-based therapy for Cancer: Celastrol, an antioxidant & anti-inflammatory drug from Thunder of God vine, increases the expression of FBXO11 via down regulation of its target gene, 22/January/2015, 17.47, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests, for the first time, that Celastrol, by suppressing the expression of its target gene, it may promote the activity of tumor suppressor FBXO11. Thus, pharmacological formulations encompassing “Celastrol or its analogues” may be used to inhibit the progression of tumors.
Amount: $ 300
Undisclosed information: How Celastrol increases the expression of FBXO11.
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