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A study from the University of California, La Jolla, CA, USA shows that Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of Nature Medicine by Prof. Thistlethwaite PA, Li X and others.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: MiRNA-based therapy for pulmonary arterial hypertension: Apurinic/Apyrimidinic Endonuclease inhibits the development of pulmonary arterial hypertension via up regulation of its target gene. Together, pharmacological formulations encompassing “Apurinic/Apyrimidinic Endonuclease activators” may be used to treat pulmonary arterial hypertension.

Amount: $ 500*

Undisclosed information: How Apurinic/Apyrimidinic Endonuclease decreases pulmonary arterial hypertension

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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To citeBoominathan, MiRNA-based therapy for pulmonary arterial hypertension: Apurinic/Apyrimidinic Endonuclease inhibits the development of pulmonary arterial hypertension via up regulation of its target gene, 29/November/2014,  22.32,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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* Research cooperation


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