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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Mechanistic insight into tumorigenesis: IL-17 increases the expression of Bcl2, a positive regulator of survival, via down regulation of its target gene, 11/February/2015, 22.15, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests that IL-17, by decreasing the expression of its target gene, it may increase the expression of Bcl2.  Thereby, it may promote survival of cancer cells. Thus, pharmacological formulations encompassing “IL-17 inhibitors  may be used to inhibit the proliferation of cancer cells.

Amount: $ 200

Undisclosed information: How IL-17 increases the expression of Bcl2

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