Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, L., Curry your way to a Longer and healthier lives: Curcumin, the major component of yellow curry powder turmeric, may prolong mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 5/April/2014, 13.14, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: It has been shown earlier that angiotensin II type I receptor (AT1R) antagonist prolongs mammalian life span. This study suggests, for the first time, that Curcumin, by increasing the expression of its target gene, it may suppress the expression of AT1R. And, thereby, it may (1) decrease blood pressure; and (2) and extend the lifespan of an individual. Thus, pharmacological formulations encompassing “Curcumin or its analogues” may be used to extend the life-span of an individual.
Undisclosed information: How Curcumin suppresses the expression of angiotensin II type I receptor (AT1R)