Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, L., Small RNAs as Lifespan extenders: MiRNA Let-7b extends life span by down regulating the expression of Growth hormone receptor, 21/May/2015, 23.32, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests, for the first time, that Let-7b , by increasing the expression of its target gene, it may suppress the expression of Growth hormone receptor. Thereby, it may increase the lifespan of an individual. Thus, pharmacological formulations encompassing “ Let-7b or its activators“ may be used to extend the life-span of an individual.
Undisclosed information: How Let-7b suppresses the expression of Growth hormone receptor.