Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Significance: AntagomiR-based therapy for augmentation of antiviral immunity: Stress-induced MiRNA miR-143 inhibits formation of germinal centers, and inhibits generation of plasma B cells upon viral infection, via downregulation of its target gene. Thus, pharmacological formulations encompassing “Anti-miR-143 or inhibitors of miR-143“ may be used to augment antiviral humoral immunity.
Amount: $ 500
Undisclosed information: How miR-143 inhibits formation of germinal centers, and inhibits generation of plasma B cells upon viral infection
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To cite: Boominathan, AntagomiR-based anti-hypertensive therapy: Anti-miR-142 suppresses angiotensin II-induced vascular remodelling and hypertension via up regulation of its target gene, 21/January/2014, 06.29 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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