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Idea Proposed/Formulated byDr L Boominathan Ph.D.

Significance: AntagomiR-based therapy for augmentation of antiviral immunity: Stress-induced MiRNA miR-143 inhibits formation of germinal centers, and inhibits generation of plasma B cells upon viral infection, via downregulation of its target gene. Thus, pharmacological formulations encompassing Anti-miR-143 or inhibitors of miR-143 may be used to augment antiviral  humoral immunity.

Amount: $ 500

Undisclosed information: How miR-143 inhibits formation of germinal centers, and inhibits generation of plasma B cells upon viral infection

Web: http://genomediscovery.org

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To citeBoominathan, AntagomiR-based anti-hypertensive therapy: Anti-miR-142 suppresses angiotensin II-induced vascular remodelling and hypertension via up regulation of its target gene, 21/January/2014,  06.29 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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