Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, AntagomiR-based therapy for DM: MIRNA-134 decreases insulin-secreting cell mass and function via down ruglation of its target gene, 23/September/2014, 06.46 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests, for the first time, that MiRNA-134, by decreasing the expression of its target gene, it may increase insulin-secreting cell mass. Thereby, it may increase the insulin sensitivity. Thus, pharmacological formulations encompassing “AntagomiR-134 or miR-134 inhibitor” may be used to treat DM.