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A recent study from Division of Pharmacology, Department Neuroscience, School of Medicine, Federico II University, Italy shows that “MicroRNA-103-1 Selectively Downregulates Brain NCX1 and Its Inhibition by Anti-miRNA Ameliorates Stroke Damage and Neurological Deficits.” This study was published in the July 22  2014 Molecular Therapy  by Prof  Pignataro Giuseppe, Antonio Vinciguerra, and others.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: MiRNA-based therapy for Stroke and Neurological deficits: MiRNA-125b ameliorates stroke damage and neurological deficits via up regulation of brain Na+/Ca2+ exchanger  (NCX1)This study suggests that miRNA-125b, by increasing the expression of NCX-1, it may ameliorate brain damage and neurological deficits Together, this study suggests that pharmacological formulations encompassing“miR-125b activators” may be used to treat patients suffering from stroke and neurological deficits.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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To citeBoominathan, MiRNA-based therapy for Stroke and Neurological deficits: MiRNA-125b ameliorates stroke damage and neurological deficits via up regulation of brain Na+/Ca2+ exchanger  (NCX1), 14/August/2014,  19.33,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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