Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, L., Anti-metastasis therapy: BMP4 inhibits epithelial-mesenchymal transiton and ZEB2 expression via up regulation of its target gene, 10/October/2014, 22.36, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that tumor suppressor BMP4, by increasing the expression of its target gene, it may decrease the expression of EMT protein ZEB2. Therefore, pharmacological formulations encompassing “BMP4 activators“ may be used to metastatic cancers.