Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, L., Antimetastasis therapy: Neurotensin (NT) inhibits migration, invasion and metastasis via down regulation of phosphodiesterase 7A (PDE7A), 11/May/2015, 23.48, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance:
This suggests that Neurotensin (NT), by increasing the expression of its target gene, it may suppress the expression of PDE7A. Thereby, it may inhibit metastatic progression of human tumors. Thus, pharmacological formulations encompassing “Neurotensin (NT) activators“ may be used to inhibit the progression of tumors.
Undisclosed information: How Neurotensin (NT) suppresses the expression of PDE7A
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