Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, Antiviral therapy: p53 inhibits Hepatitis B Virus Transcription via up regulation of its target gene, 28/October/2014, 22.24, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Undisclosed information: A mechanistic insight into How p53 inhibits Hepatitis B Virus Transcription.
Significance: This study suggests, for the first time, that tumor suppressor p53, by increasing the expression of its target gene, it may inhibit Hepatitis B Virus Transcription. Thus, pharmacological formulations encompassing “p53 activators” may be used to inhibit Hepatitis B Virus Transcription.