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May 3, 2015

Natural product-based therapy for Muscle wasting and Cancer cachexia: Fisetin, a flavonoid enriched in strawberries, Mangoes and Cucumber, inhibits muscle fiber atrophy during cancer cachexia and sepsis and promotes muscle growth via up regulation of its target gene, 3/May/2015, 12.19 pm

Significance: It has been shown that muscle atrophy is associated with a number of disease conditions, including Cancer cachexia. This study suggests, for the first time, that Fisetin, […]
May 3, 2015

Natural product-based therapy for pulmonary diabetic cardiomyopathy: Agaricus blazei Murill (AbM), a medicinal mushroom, inhibits the development of diabetic cardiomyopathy via down regulation of its target gene Foxo1, 3/May/2015, 09.19 am

A study from the Department of Internal Medicine (Cardiology), University of Texas Southwestern Medical Center, Dallas, Texas 75390-8573, USA shows that “Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice.” This […]
May 3, 2015

Molecular therapy for Human Cancer: Suppressor of cytokine signaling 1 (SOCS1) suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene, 3/May/2015, 7.53 am

The 1989 Noble prize winner in Chemistry, Prof. Thomas R. Cech, from the University of Colorado BioFrontiers Institute, USA, has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The […]
May 2, 2015

Regenerating the lost cardiomyocytes in Myocardial patients: FRA1 increases the expression of ERBB2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 3/May/2014, 12.39 am

A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
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