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May 5, 2015
Published by admin_auro at May 5, 2015
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Repairing the damaged DNA by exposing it to the Sunlight: Calcitriol (1α, 25-dihydroxyvitamin D3) increases the expression of DNA repair protein hMSH2 and inhibits tumor development via down regulation of its target gene, 5/May/2015, 22.34

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests a vitamin-based Anti-cancer therapy. 1α, 25-dihydroxyvitamin D3 (Calcitriol), by increasing the expression of its target genes, […]
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May 5, 2015
Published by admin_auro at May 5, 2015
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Small molecule-based therapy for p53-deficient tumors: BMP4 suppresses & increases the expression of DNp63α & IAPP (Amylin), respectively, and induces regression of p53-mutated human tumors via down regulation of its target gene, 5/May/2015, 17.43

A recent study from the Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA [2] […]
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May 5, 2015
Published by admin_auro at May 5, 2015
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Molecular therapy for Metastatic human tumors: Ndfip1 inhibits cellular proliferation, invasion and metastasis by increasing the expression of tumor suppressor TAp63 via down regulation of its target gene, 5/May/2015, 17.26

A study from the Cell Pathology Division, The Children’s Hospital of Philadelphia, Philadelphia, USA shows that “TGF-β induces the expression of the adaptor Ndfip1 to silence IL-4 production […]
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May 5, 2015
Published by admin_auro at May 5, 2015
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Mechanistic insight into tumorigenesis: Orphan Nuclear receptor NUR77 increases the expression of oncomiR miRNA-17-92 via up regulation of its target gene, 5/May/2015, 17.00

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Mechanistic insight into tumorigenesis: Orphan Nuclear receptor NUR77 increases the expression of oncomiR miRNA-17-92 via up regulation of […]
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