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April 24, 2015

Stalling metastatic cancer spread by exposing it to the Sunlight: Calcitriol (1α, 25-dihydroxyvitamin D3) increases the expression of tumor suppressor RECK and inhibits migration and invasion of metastatic cancer cells via down regulation of its target gene, 24/April/2015, 12.20 pm

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests a vitamin-based Anti-metastasis therapy. 1α, 25-dihydroxyvitamin D3 (Calcitriol), by increasing the expression of its target genes, […]
April 24, 2015

Natural product-based therapy for pulmonary arterial hypertension: Cinnamaldehyde (CA) inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 24/April/2015, 7.59 am

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in […]
April 24, 2015

Molecular therapy for Human Cancer: GATA3 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene, 24/April/2015, 7.54 am

The 1989 Noble prize winner in Chemistry, Prof. Thomas R. Cech, from the University of Colorado BioFrontiers Institute, USA, has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The […]
April 24, 2015

Regenerating the lost cardiomyocytes in myocardial patients: Unacylated ghrelin (UnAG) improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 24/April/2014, 7.47 am

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On […]
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