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May 1, 2015

Stretch therapy for pulmonary arterial hypertension: Mechanical stretch inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 1/May/2015, 9.01 am

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in […]
April 30, 2015

The Exercise-Mimicking pills may inhibit Insulin resistance and decrease adiposity: BMB4 decreases gluconeogenesis genes, such as PEPCK and G6Pase, reduces hepatic glucose production, improves muscle insulin sensivitity and decreases adiposity via up regulation of its target gene, 1/May/2015, 12.19 am

Significance: This study suggests, for the first time, that BMP4, by increasing the expression of its target gene, it may: (1) decrease the expression of gluconeogenesis genes, such […]
April 30, 2015

Turning on senescence turns off cancer progression: HIF-1α inhibits telomere dysfunction and senescence via up regulation of Telomeric repeat binding factor 2 (TRF2), 30/April/2015, 23.57

A recent study from the Key Laboratory of Gene Engineering of the Ministry of Education, Key Laboratory of Reproductive Medicine of Guangdong Province, School of Life Sciences […]
April 30, 2015

Natural product-based therapy for Regenerating the lost cardiomyocytes in Myocardial patients: SNAI, an activator of epithelial-mesenchymal transition, increases the expression of ERBB2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 30/April/2014, 23.37

A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
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