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April 27, 2015
Published by admin_auro at April 27, 2015
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Sunlight exposure stalls Cancer stem cell proliferation and metastatic cancer progression: Calcitriol (1α, 25-dihydroxyvitamin D3) decreases the expression of cancer stem-cell enriched reprogramming protein Nanog and inhibits migration and invasion of metastatic cancer cells via down regulation of its target gene, 27/April/2015, 8.33 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests a vitamin-based Anti-cancer stem cell/metastasis therapy. 1α, 25-dihydroxyvitamin D3 (Calcitriol), by increasing the expression of its […]
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April 27, 2015
Published by admin_auro at April 27, 2015
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The Exercise-Mimicking pills may inhibit Insulin resistance and decrease adiposity: HMGB1 decreases gluconeogenesis genes, such as PEPCK and G6Pase, reduces hepatic glucose production, improves muscle insulin sensivitity and decreases adiposity via up regulation of its target gene, 27/April/2015, 8.01 am

Significance: This study suggests, for the first time, that HMGB1, by increasing the expression of its target gene, it may: (1) decrease the expression of gluconeogenesis genes, such […]
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April 27, 2015
Published by admin_auro at April 27, 2015
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Molecular therapy for Metastatic human tumors: Ndfip1 decreases cellular proliferation, invasion and metastasis by increasing the expression of metastasis suppressor TIMP3 via down regulation of its target gene, 27/April/2015, 7.00 am

A study from the Cell Pathology Division, The Children’s Hospital of Philadelphia, Philadelphia, USA shows that “TGF-β induces the expression of the adaptor Ndfip1 to silence IL-4 production […]
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April 26, 2015
Published by admin_auro at April 26, 2015
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Natural product-based therapy for Metastatic Pancreatic/intestine/ovarian Cancers: Curcumin, the major component of turmeric, suppresses the expression of PDGF Receptor β (PDGFRβ) via down regulation of its target gene, 27/April/2015, 12.20 am

A study from Watson School of Biological Sciences shows that Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling. This study was published in the April 10, […]
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