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April 27, 2015
Published by admin_auro at April 27, 2015
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Small RNAs not only cure T2DM, but also extend lifespan: MiRNA-216b increases UCP protein expression, energy expenditure, glucose tolerance, insulin sensitivity and extends lifespan via down regulation of its target gene, 27/April/2015, 10.48 am

A study from the Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Diabetes Unit, Medical Services, Massachusetts General Hospital, Boston, MA 02114, USA; […]
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April 27, 2015
Published by admin_auro at April 27, 2015
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Sunlight exposure stalls Cancer stem cell proliferation and metastatic cancer progression: Calcitriol (1α, 25-dihydroxyvitamin D3) decreases the expression of cancer stem-cell enriched reprogramming protein Nanog and inhibits migration and invasion of metastatic cancer cells via down regulation of its target gene, 27/April/2015, 8.33 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests a vitamin-based Anti-cancer stem cell/metastasis therapy. 1α, 25-dihydroxyvitamin D3 (Calcitriol), by increasing the expression of its […]
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April 27, 2015
Published by admin_auro at April 27, 2015
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The Exercise-Mimicking pills may inhibit Insulin resistance and decrease adiposity: HMGB1 decreases gluconeogenesis genes, such as PEPCK and G6Pase, reduces hepatic glucose production, improves muscle insulin sensivitity and decreases adiposity via up regulation of its target gene, 27/April/2015, 8.01 am

Significance: This study suggests, for the first time, that HMGB1, by increasing the expression of its target gene, it may: (1) decrease the expression of gluconeogenesis genes, such […]
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April 27, 2015
Published by admin_auro at April 27, 2015
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Molecular therapy for Metastatic human tumors: Ndfip1 decreases cellular proliferation, invasion and metastasis by increasing the expression of metastasis suppressor TIMP3 via down regulation of its target gene, 27/April/2015, 7.00 am

A study from the Cell Pathology Division, The Children’s Hospital of Philadelphia, Philadelphia, USA shows that “TGF-β induces the expression of the adaptor Ndfip1 to silence IL-4 production […]
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