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April 25, 2015
Published by admin_auro at April 25, 2015
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MiRNA-based Exercise-Mimicking pill may inhibit Insulin resistance: MiRNA-582-5p decreases gluconeogenesis genes, such as PEPCK and G6Pase, reduces hepatic glucose production, and improves insulin sensivitity via down regulation of its target gene, 25/April/2015, 22.05

Significance: This study suggests, for the first time, that MiRNA-582-5p, by decreasing the expression of its target gene, it may: (1) decrease the expression of gluconeogenesis genes, such […]
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April 25, 2015
Published by admin_auro at April 25, 2015
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Natural product-based Regenerative therapy for T2D: Cilostazol promotes reprogramming of adult pancreatic ductal cells into α, δ, and β cells via up regulation of Ngn3, 25/April/2015, 21.53

A recent study from the Mammalian Genetics Laboratory, Cancer Research UK London Research Institute, Lincoln’s Inn Fields Laboratories, London, United Kingdom; and School of Medicine, King’s College […]
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April 25, 2015
Published by admin_auro at April 25, 2015
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Regenerative therapy for Diabetes mellitus: PAPD5 increases human pancreatic beta cell replication via down regulation of its target gene DYRK1A, 25/April/2015, 21.45

A study from the Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA and Division of Endocrinology and Bone […]
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April 25, 2015
Published by admin_auro at April 25, 2015
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MiRNA-based therapy for Preserving β-Cell functioning in DM and for extending life span of humans: MiRNA-337-3p increases the expression of antiaging and longevity gene Klotho, improves β-Cell function and prevents the development of T2DM via down regulation of its target gene, 25/April/2015, 21.12

Significance:   Given that (1)  more than 387 million people worldwide are affected by Diabetes mellitus (DM); (2) the life-long painful injection/drug treatment is required to treat DM; […]
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