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February 5, 2015

Natural product-based therapy for pulmonary arterial hypertension: Honokiol, a natural compound derived from the bark of the Magnolia officinalis tree, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene, 6/February/2015, 02.29 am

A study from the University of California, La Jolla, CA, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of Nature Medicine by Prof. Thistlethwaite PA, Li X and others. On the foundation […]
February 4, 2015

Molecular therapy for Pulmonary Hypertension (PAH): Tumor suppressor p53 inhibits pulmonary hypertension via induction of PDLIM5, 4/February/2015, 23.20

Significance: This study suggests, for the first time, that p53, by suppressing the expression of its target gene, it may increase the expression of PDLIM5. Thereby, […]
February 4, 2015

Mechanistic insight into tumorigenesis: Tudor Staphylococcal Nuclease protein suppresses the expression of tumor suppressor TPM1 via down regulation of its target gene, 4/February/2015, 23.00

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Mechanistic insight into tumorigenesis: Tudor Staphylococcal Nuclease protein suppresses the expression of tumor suppressor TPM1 via down regulation of […]
February 4, 2015

Preserving the function of the guardian of the genome, p53: Rubone inhibits functional inactivation of p53 by somatic mutation and viral oncognes via up regulation of its target gene, 4/February/2015, 22.57

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Preserving the function of the guardian of the genome, p53:  Rubone inhibits functional inactivation of p53 by somatic […]
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