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February 4, 2015

Molecular therapy for Stroke: I3C inhibits cerebral ischemia induced injury via up regulation of its target gene, 4/February/2015, 22.00

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Molecular therapy for Stroke:  I3C, a natural product of Brassica vegetables, inhibits cerebral ischemia induced injury via […]
February 4, 2015

Natural product-based therapy for Human Cancer: Cirsilol suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene, 4/February/2015, 21.45

The 1989 Noble prize winner in Chemistry, Prof. Thomas R. Cech, from the University of Colorado BioFrontiers Institute, USA, has published a research paper in the 13 December 2012 Nature (492(7428):285-9; I.F: >35) stating that “The TEL […]
February 4, 2015

Natural product-based therapy for pulmonary arterial hypertension: Chlorogenic acid inhibits the development of pulmonary arterial hypertension via up regulation of its target gene, 4/February/2015, 9.44 am

A study from the University of California, La Jolla, CA, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of Nature Medicine by Prof. Thistlethwaite PA, Li X and others. On the foundation […]
February 4, 2015

MiRNA based cancer therapy: MiRNA-29 inhibits cancer development by decreasing the expression of nucleotide sanitizing enzyme MTH1/NUDT1, 4/February/2014, 9.15 am

A study from Karolinska Institutet, Stockholm, Sweden shows that MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.  This study was published in the April 10, 2014 Nature [I.F >42] by Prof. Thomas H, […]
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