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April 6, 2015

Natural product-based therapy for p53-deficient tumors: Asprin [acetylsalicylic acid (ASA)] suppresses and increases the expression of DNp63α and IAPP(Amylin), respectively, and induces regression of p53-mutated human tumors via down regulation of its target gene, 6/April/2015, 22.38

A recent study from the [1] Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA; [2] […]
April 6, 2015

Small molecule-based Life-span extension therapy: AICAR, an analog of AMP, inhibits senescence and extends life span by down regulating the expression of adenylate cyclase 5 (ADCY5), 6/April/2015, 17.41

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Small molecule-based Life-span extension therapy: AICAR, an analog of AMP, inhibits senescence and  extends life span […]
April 6, 2015

Immune enhancement therapy: AICAR, an analog of AMP, increases SOX2 expression and promotes innate immunity against bacterial infection, 6/April/2015, 17.33

A recent study from the Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor […]
April 6, 2015

Molecular therapy for pulmonary arterial hypertension: AICAR, an analog of AMP, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene, 6/April/2015, 17.07

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in […]
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