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April 19, 2015
Published by admin_auro at April 19, 2015
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Sunlight exposure stalls p53-mutated metastatic cancer progression: Calcitriol (1α, 25-dihydroxyvitamin D3) increases the expression of tumor suppressor p53 homolouge TAp63 and inhibits migration and invasion of metastatic cancer cells via down regulation of its target gene, 19/April/2015, 10.43 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance:  Cancer suppressor p53 is mutated in more than 50% of human cancers of different origin, while its pathway […]
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April 19, 2015
Published by admin_auro at April 19, 2015
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Small molecule-based Life-span extension therapy: Endothelin-1 (ET-1) inhibits senescence and extends life span by down regulating the expression of adenylate cyclase 5 (ADCY5), 19/April/2015, 10.37 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Small molecule-based Life-span extension therapy: Endothelin-1 (ET-1) inhibits senescence and  extends life span by down regulating […]
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April 19, 2015
Published by admin_auro at April 19, 2015
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Immune enhancement therapy: ARID3B (AT rich interactive domain 3B) increases SOX2 expression and promotes innate immunity against bacterial infection via down regulation of its target gene, 19/April/2015, 06.16 am

A recent study from the Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor […]
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April 19, 2015
Published by admin_auro at April 19, 2015
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Rescuing the malfunctioning cardiomyocytes in myocardial patients: E3 ubiquitin ligase RNF2 (ring finger protein 2) improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 19/April/2014, 06.09 am

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On […]
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