Insights into mechanisms that dysregulate the tumor suppressor networks in human cancer cells: RREB increases the expression of oncogenic protein SPOP via down regulation of its target gene, 28/June/2014, 9.36 am
A recent study from University of Chicago (Illinois, USA) shows that “SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub…” This study was published in the prestigious Journal Cancer Cell (One of the high profile journals in cancer biology with an I.F of 24.755) by Prof White KP, Dr Li G and others from the Institute for Genomics and Systems Biology, University of Chicago and Argonne […]
MiRNA-based cancer therapy: MiRNA-99 inhibits cancer development by suppressing the expression of nucleotide sanitizing enzyme MTH1/NUDT1, 28/June/2014, 9.20 am
A study from Karolinska Institutet, Stockholm, Sweden shows that MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. This study was published in the April 10, 2014 Nature [I.F >35] by Prof. Thomas H, Dr Gad H and others from Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden. On the foundation of this […]
Sirtuin-2 activators as anti-hypertensive agents: Sirtuin-2 attenuates pulmonary hypertension via up regulation of dimethylarginine dimethylaminohydrolases (DDAH1), 28/June/2014, 8.26 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, L., Sirtuin-2 activators as anti-hypertensive agents: Sirtuin-2 attenuates pulmonary hypertension via up regulation of dimethylarginine dimethylaminohydrolases (DDAH1), 28/June/2014, 8.25 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation
Therapeutic Insights into Ischemic Stroke: MiRNA-17-5p alleviates cerebral ischemic injury through enhancing beclin 1-mediated autophagy, 28/June/2014, 6.56 am
Idea Proposed/Formulated by: Dr L Boominathan PhD Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Therapeutic Insights into Ischemic Stroke: MiRNA-17-5p alleviates cerebral ischemic injury through enhancing beclin 1-mediated autophagy, 28/June/2014, 6.56 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation
S100A4 suppresses the expression of physiological mutator Activation-induced (cytidine) deaminase (AID) via up regulation of its target gene, 28/June/2014, 6.37 am
Idea Proposed/Formulated by: Dr L Boominathan PhD Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, S100A4 suppresses the expression of physiological mutator Activation-induced (cytidine) deaminase (AID) via up regulation of its target gene, 28/June/2014, 6.37 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation
Insights into the treatment of allergen-induced tumorigenesis: Allergen suppresses the expression of pro-apoptotic protein BTG2 via up regulation of its target gene, 27/June/2014, 6.13 am
Idea Proposed/Formulated by: Dr L Boominathan PhD Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Insights into the treatment of allergen-induced tumorigenesis: Allergen suppresses the expression of pro-apoptotic protein BTG2 via up regulation of its target gene, 27/June/2014, 6.13 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation