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January 22, 2015

MiRNA-based Neuron replacement therapy for Neurodegenerative diseases: miR-375 promotes neuronal conversion from differentiated cells via down regulation of its target gene, 22/November/2014, 09.00 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Significance: This study suggests that miR-375, by suppressing the expression of its target gene, it may convert the differentiated cells […]
January 22, 2015

Consume chocolates to protect yourself from Myocardial Infarction: Theobromine/xantheose, derived from theobroma and commonly found in chocolates, improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 22/December/2014, 8.40 am

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature [I.F: >42] by Prof Dimmler, Boon, and […]
January 22, 2015

Natural product-based Life-extension therapy: Baicalein (5,6,7-Trihydroxyflavone), an active component of Scutellaria baicalensis, may increase life span by suppressing its target gene, 22/November/2014, 06.24 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Significance: Natural product-based Life-extension therapy: Baicalein (5,6,7-Trihydroxyflavone), an active component of Scutellaria baicalensis, may increase life span by suppressing its target […]
January 22, 2015

Natural product-based therapy for pulmonary arterial hypertension: Baicalein (5,6,7-Trihydroxyflavone), an active component of Scutellaria baicalensis, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene, 22/November/2014, 5.50 am

A study from the University of California, La Jolla, CA, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of Nature Medicine by Prof. Thistlethwaite PA, Li X and others. On the foundation […]
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